Porziņģis scored 16 points in 36:51 on the court, scoring three of five three-point shots, one of five two-pointers and all five free throws.
Meanwhile Bertāns scored a three-pointer in 13:41 on court.
Carmelo Anthony scored 25 points and Derrick Rose scored 18 for the Knicks.
The Spurs' Kawhi Leonard was the game's lead scorer with 36 points.
For the first time in @NBA history two Latvian players are on the court at the same time. (CC: @DBertans_42 @kporzee)
— San Antonio Spurs (@spurs) February 12, 2017
REPLAY: @kporzee says ? #NYKvsSAS #Knicks pic.twitter.com/iHezbO8q4W
— NEW YORK KNICKS (@nyknicks) February 12, 2017
The next duel between the two teams with Latvian players will take place on March 27 in San Antonio.
