Straujuma will visit Alsace on Sunday at French President Francois Hollande's invitation as a representative of the EU presidency.
The event will be held to mark the 70th anniversary of the liberation of the concentration camp. Hitler's regime opened the camp in 1940 in Alsace, a territory in eastern France annexed by Germany, to imprison deportees from Europe's occupied territories.
Over 50,000 prisoners were enslaved and some 20,000 died at the Natzweiler-Struthof concentration camp between 1941 and 1945. There were around 400 Latvians among the various nationalities imprisoned at the camp.
Other officials expected to attend the commemorative event include European Council President Donald Tusk, Council of Europe Secretary General Thorbjorn Jagland and European Parliament President Martin Schulz.
On Monday, April 27, Straujuma is scheduled to have a bilateral meeting with Hollande in Paris.